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An in vivo mouse experiment using the syngeneic mouse oral cancer line (MOC1) with and without activating NRF2 E79Q mutations demonstrated that NRF2 E79Q mutation was associated with radiation resistance, an effect more pronounced in immune competent mice [54]

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doi: 10.1016/j.mri.2022.02.003 247 PengJQiuCZhangJXiaoX